Job Description:
Principal Scientist, Cell Biology

A San Diego venture capital backed company developing rare-cell diagnostic systems to address significant unmet medical needs. We provide outstanding career opportunities for innovative and motivated team players who are committed to making a difference in science and human healthcare.

We are searching for an experienced professional to join our growing, dynamic team!
The ideal candidate will have the following areas of expertise: Cell Biology, Biochemistry, Hematopoiesis, Antibody Optimization, Flow Cytometry and Magnetic Cell Selection.

This scientist will lead a team and interact with a multidisciplinary group of Cell Biology, Biochemistry, and Engineering scientists to develop novel cell enrichment techniques and assays. The hands-on scientist will design, manage and directly execute the enrichment of novel rare-cell populations from blood. Responsibilities will include research, experimental planning, and execution through hands-on experimentation, and direction of a group of research associates. This person will also be responsible for analysis, summary and presentation of data to other scientists and senior management.

Requirements and Qualifications:

• PhD and a minimum of 5 years relevant scientific and project lead experience required.
• Extensive experience with methods of magnetic-bead based separation and flow- cytometry, including analysis and FACS for the identification and/or isolation of rare cell populations such as hematopoietic lineages, tumor, or stem cells required.
• Experience with biochemistry of cell labeling and antibody staining required.
• Experience with antibody selection, conjugation chemistries, and specificity validation required.
• Familiarity with the current developments in stem cells research in terms of identification, separation, and potential for clinical applications required.
• Demonstrated ability to successfully complete complex projects with challenging timelines.
• Developed novel assays or cell enrichments in a product development or clinical setting a plus.
• Function independently and work on multidisciplinary team-based projects required.
• Experience with PCR; Q-PCR/Real-time PCR experience a plus.
• Excellent written and verbal communication skills required.